

Mooppan Raghavan, tribal leader of Thalikakal settlement in Kerala, and over a dozen members of his tribe were recruited as extras. His editing credit is misrepresented on preliminary on-line posters as "Anthony Ciccone." The film is edited by American editor Tony Ciccone, who is also credited with additional sound design. It was also shot in Mumbai, Chennai, Madh Island, and in the studios of Filmistan. Hisss was shot in the jungle of Kerala, India. Famed special effects designer Robert Kurtzman was responsible for developing the look of the Snake Woman. The film was shot simultaneously in English and Hindi. Divya Dutta as Maya Gupta, inspector's wife.Irrfan Khan as Inspector Vikram Gupta.He returns to his wife Maya, who later gives birth to their baby, while the nagin, back in the form of a beautiful woman, watches over the nest of eggs she has laid, which hatch into numerous baby cobras. Inspector Gupta is amazed at everything he has just witnessed. She leaves the hideout, carrying her dead mate. Angered by the death of her mate by the hands of George, the nagin turns into a half snake, half human hybrid creature and throws him in the glass box where her mate was kept and electrocutes him to death. He captures her and tries taking the nagmani, but at that moment, Inspector Gupta arrives and helps her.

Wearing a suit that hides his heat signature, he lures her by using her dying mate as bait to a trap. George attempts to capture the nagin during intercourse since this is when she will be most vulnerable. Finally, the Nagin reaches George's hideout where she reclaims her mate and they have sex, leading her to becoming pregnant. Inspector Gupta tries to help the nagin find her mate, but at the same time, tries to investigate the murders, unaware she is responsible for them. She turns back into a human after her killings. She turns into a giant cobra and brutally kills those two men, some of George States’ henchmen who were involved in the capture of her mate as well as men who torture women. She even helps herself when two men try to rape her. The nagin helps a few women who are helpless: One who is beaten mercilessly by her husband one being raped by a man, and so on. The nagin transforms into a beautiful woman ( Mallika Sherawat), and is later helped by police inspector Vikram Gupta ( Irrfan Khan) and his wife, Maya ( Divya Dutta), who is infertile, causing a strain in their relationship. His plan works and the nagin starts following them.

He keeps the nag in a glass box where he electrocutes and tortures him.

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He and hired henchmen capture the nag (the male snake) so that the nagin (the female) comes after the capturer to free her mate, thus allowing him to obtain the nagmani by force. To prevent death and gain immortality, he decides to extract the "Nagmani" immortal blood from a nagin, a shape-shifting cobra that can change into a human. George States ( Jeff Doucette) is suffering from the last stage of brain cancer and has only six months to live. The story begins in Natchi, a small town in the Indian state of Kerala.
